12 Best Probiotic Supplements of 2025, According to Dieticians



Best for Digestion: Garden of Life Once Daily Women’s Probiotic

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Garden of Life

Once Daily Women’s Probiotic

Why We Love It: For Syn, this probiotic by Garden Of Life is specifically formulated to support women’s health with clinically studied strains that target digestive, immune and vaginal health—making it “a good option for women who experience recurring urinary tract infections, yeast infections or digestive irregularities who want targeted support.” Drawing up on 16 probiotic strains with 50 billion CFU, the capsule has received the approval of Berjis, recommending it for women dealing with bloating, stress, hormonal shifts, or post-antibiotic recovery. “It’s wellness in a capsule, no fancy fridge required,” she says.


Best Synbiotic: Seed DS-01 Daily Synbiotic

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Why We Love It: Seed is another ultra-popular probiotic supplement on the market right now—and for good reason. This synbiotic supplement (which means it contains both prebiotics and probiotics) is formulated to support the gut and whole body health, with the help of 24 bacteria strains. “Probiotic diversity is critical for overall health,” says Ella Davar, RD, founder of Gut-Brain Method. “Products like Seed DS-01, which offer multi-strain formulations, are excellent for increasing diversity.”


Best for Women’s Health: Wisp Basic Probiotics

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Why We Love It: When we asked Lucky Sekhon, MD, a double-board certified reproductive endocrinologist, infertility specialist, obstetrician and gynecologist, about her favorite probiotics for women, she recommended this one by Wisp. “It contains a variety of beneficial bacteria strains that work together to promote overall wellness, enhance digestive health, and maintain a healthy balance of vaginal flora,” she says. “This supplement is particularly great for its dual-action benefits, making it a convenient option for comprehensive health support.”


Best for Metabolism: Pendulum Metabolic Daily

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Why We Love It: According to registered dietitian nutritionist and founder of Compass Nutrition Adiana Castro, RD, “many of my patients have low energy and struggle with bloating, especially my female patients right before and during their menstrual cycle.” Which is where Pendulum Metabolic Daily comes in. Each capsule contains five probiotic strains to improve metabolism, strengthen the gut lining, reduce bloating, and maintain a healthy weight.


Best for Vaginal Health: Hum Nutrition Private Party Vaginal Probiotic

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Hum Nutrition

Private Party Vaginal Probiotic

Why We Love It: If you’re in search of a probiotic that prioritizes both vaginal and urinary tract health, consider Hum Nutrition’s Private Party your go-to. In just one capsule per day, this delivers 10 billion CFUs through three strains of probiotics; specifically, lactobacillus acidophilus—a well-researched strain that promotes a healthy vaginal environment, plus lactobacillus rhamnosus and lactobacillus reuteri, which balance the body’s pH. Cranberry extract is featured too for positive urinary benefits.



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