Housed in a circa 14th-century monastery, this sprawling property is well-positioned in the heart of the city and offers 99 rooms and suites to choose from. Period details—like vaulted ceilings and original parquet flooring—dot the hotel, and some of the guest rooms overlook the tranquil monastery garden. From June to September, you can sit outside on a sunny terrace at the Monastiq restaurant, which serves up contemporary Czech dishes. The real highlight, though, has to be the spa: It’s located in a former Renaissance chapel, where glass floors reveal Gothic ruins.

• Amenities: Spa, fitness center, on-site restaurant, bar, meeting spaces, sauna
• Bonus Tip: Pre-spa treatment, unwind in the tea lounge with a cup of herbal tea to get in the relaxation mindset.
• Address: Nebovidská 459/1, Malá Strana, Prague, 118 00

Courtesy of Sir Prague

Bordering Prague’s New Town by the Vltava river, Sir Prague opened its doors earlier this year and is already making a name for itself. This is in no small part due to the design: Courtesy of Linda Boronkay (the former design director of Soho House), each of the 76 rooms both references the traditional charm of the city and gives it its own flair. (The zellige terracotta-and-burgundy tiling and matching marble in the bathroom feels decidedly current; the ancient wood beams in the bedroom bordering it, less so.) After a day of sightseeing, unwind in the cozy, Murano chandelier-lit library, or head outside to the quiet courtyard to grab a bite.