Its Monday, May 12 and the Marlins (15-24) are in Chicago to take on the Cubs (23-18).

Cal Quantrill is slated to take the mound for Miami against Colin Rea for Chicago.

The NL Central-leading Cubs have lost four of their last six games including two of three to the Mets over the weekend. Chicago’s bullpen wilted yesterday allowing four runs in the eighth inning in a 6-2 loss to New York. The Cubs’ offense was nearly non-existent allowing just three hits. One of the three, though, was Pete Crow-Armstrong’s tenth home run of the season.

Miami has also lost four of their last six. This weekend they lost two of three to the White Sox in Chicago. Sunday, Xavier Edwards picked up a couple hits and drove in a run but it was not enough as the Sox took out the Marlins 4-2.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Marlins at Cubs

• Date: Monday, May 12, 2025
• Time: 7:40PM EST
• Site: Wrigley Field
• City: Chicago, IL
• Network/Streaming: FDSNFL, MARQ

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Marlins at the Cubs

The latest odds as of Monday:

• Moneyline: Marlins (+201), Cubs (-246)
• Spread: Cubs -1.5
• Total: 8.0 runs

Probable starting pitchers for Marlins at Cubs

• Pitching matchup for May 12, 2025: Cal Quantrill vs. Colin Rea
  • Marlins: Cal Quantrill (2-3, 7.11 ERA)
    Last outing: 5/6 vs. Dodgers – 5IP, 1ER, 4H, 1BB, 6Ks
  • Cubs: Colin Rea (2-0, 2.43 ERA)
    Last outing: 5/6 vs. San Francisco – 5IP, 4ER, 8H, 2BB, 4Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Marlins at Cubs

• The Cubs have a 10-4 record in series openers this season
• The Over is 4-1 in the Marlins’ last 5 games against National League teams
• The Cubs have failed to cover the Run Line in 5 of their last 7 home games
• Kyle Tucker is struggling in May hitting .237 with 9 hits in 38 ABs
• Pete Crow-Armstrong has hit in 4 straight games (4-15) and 8 of his last 9 games (9-35)

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Marlins and the Cubs

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Monday’s game between the Marlins and the Cubs:

• Moneyline: NBC Sports Bet is recommending a play on the Chicago Cubs on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago Cubs -1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
• Drew Dinsick (@whale_capper)
• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)